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Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.Isoform 1 may play a role in establishing and maintaining successful pregnancy.
Gene Name: | interleukin 22 receptor, alpha 2 |
Synonyms: | IL22RA2, Class II cytokine receptor, IL-22BP, IL-22RA2, IL-22R-alpha-2, Interleukin 22-binding protein, Interleukin-22-binding protein, CRF2-10, CRF2-S1, CRF2X, IL-22 receptor subunit alpha-2, IL22BP, ZcytoR16 |
Target Sequences: | NM_052962 NP_443194.1 Q969J5 |
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