Target
Human IL-1B / IL-1 Beta
Synonyms
IL1B | IL-1B | IL-1 beta | IL1-BETA | Preinterleukin 1 beta | Pro-interleukin-1-beta | Catabolin | IL-1 | IL1F2 | Interleukin 1, beta | Interleukin-1 beta
Reactivity
Human
(tested or 100% immunogen sequence identity)
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Immunogen
Synthetic peptide from the C-Terminus of human IL1 beta (FLGGTKGGQDITDFTMQFVSS, aa249-269 of UniProt P01584). Percent identity by BLAST analysis: Human (100%); Dog (81%); Mouse (67%); Rat (62%).
Specificity
Human IL-1B / IL-1 Beta
Applications
- Western blot (0.5 - 1 µg/ml)
Usage
Interleukin-1 beta (IL-1beta) also know as catabolin, is a cytokine protein that in humans is encoded by the IL1B gene, which localizes to the long arm of chromosome 2 at position 2q13-2q21 between two fragile sites. Interleukin 1 (IL-1) is a protein with several biological activities regulating host defense and immune responses. The human IL-1 family plays an important role in the pathogenesis of many diseases and functions as a key mediator of the host response to various infectious, inflammatory, and immunologic challenges.
Presentation
Lyophilized from PBS, 2.5% BSA, 0.025% sodium azide/thimerosal.
Reconstitution
Reconstitute in sterile distilled water.
Storage
Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee