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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IKBKB / IKK2 / IKK Beta Antibody (phospho‑Ser177/Ser181) LS‑C15901
Antibody
IKK Beta antibody LS-C15901 is an unconjugated rabbit polyclonal antibody to human IKK Beta (IKBKB / IKK2). Validated for WB.
Catalog
Size
Price
LS-C15901-100
100 µl
Unavailable

Popular IKBKB / IKK2 / IKK Beta Products

Antibody
Species: Human, Mouse, Rat
Applications: IHC, Western blot, ELISA
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Anti-IKBKB / IKK Beta antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1362 concentration 5 ug/ml.
Species: Human
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Western blot Image
Species: Human, Mouse, Rat
Applications: Western blot, Immunoprecipitation, ELISA

Product Description

IKK Beta antibody LS-C15901 is an unconjugated rabbit polyclonal antibody to human IKK Beta (IKBKB / IKK2). Validated for WB.
About IKBKB / IKK2 / IKK Beta
Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. O14920 AF080158 AAD08997.1

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Specifications

Target
Human IKBKB / IKK2 / IKK Beta
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Immunogen
Phospho-peptide corresponding to a region surrounding serines 177/181 of IKKb ((KLH-coupled) ).
Epitope
pSer177/Ser181
Specificity
Recognizes endogenous levels of human IKKb only when phosphorylated at serines 177/181. Species cross-reactivity: mouse, rat, monkey.
Usage
Suitable for use in Western Blot. Western Blot: 1:1000.
Presentation
10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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