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Anti-IKBKB / IKK2 / IKK Beta Antibody (clone 10A9B6) LS-C555

Ordering

Wt. Vol. Conc. Price
100 µg 200 µl 0.5 mg/ml $335
Inquire for larger quantities

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Mouse Monoclonal [clone 10A9B6] (IgG) to Human IKBKB / IKK2 / IKK Beta
Human, Mouse
Western blot, Immunoprecipitation
Unconjugated

Details

Human IKBKB / IKK2 / IKK Beta
Mouse
Human, Mouse (tested or 100% immunogen sequence identity)
IgG Monoclonal [10A9B6]
Protein G purified

Applications

Western blot (2 - 5 µg/ml), Immunoprecipitation (2 - 5 µg/10E6 cells)
IHC - Paraffin

Specificity and Use

IKBKB / IKK2 / IKK Beta antibody was raised against full length human IKKb/IKK2 recombinant protein.
An approx. 87 kD band should be observed.

Packaging

PBS, 0.05% BSA, 0.05% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About IKBKB / IKK2 / IKK Beta

O14920 AF080158 AAD08997.1

IKBKB Antibody, Ikk 2 Antibody, IKK-B Antibody, IKK2 Antibody, IKKbeta Antibody, NFKBIKB Antibody, I-kappa-B kinase 2 Antibody, IKKB Antibody, I-kappa-B-kinase beta Antibody, Ikb kinase-beta Antibody, IKK Beta Antibody, IKK-beta Antibody

Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome.

Western blot

Western blot
Western blot of IKKb in Daudi cell lysate using antibody at5 ug/ml.

Immunoprecipitation

Immunoprecipitation
antibody was used to immunoprecipitate IKKb from 1x10^6 Daudi cells and the immuno-precipitated protein was detected by western blotting using antibody. IKKb was detected as a protein of ~87 kD.

Requested From: United States
Date Requested: 9/29/2016

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