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Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP).
Gene Name: | Indian hedgehog |
Family/Subfamily: | Protease , Cysteine C46 |
Synonyms: | IHH, Indian hedgehog, Indian hedgehog homolog, Indian hedgehog protein, HHG2, BDA1, HHG-2 |
Target Sequences: | BC034757 Q14623 Q14623 |
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