Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone JBW902] (IgG2a) to Human IGF1R / IGF1 Receptor
IHC - Paraffin, Western blot, Immunoprecipitation
Mouse Monoclonal (IgG1) to Human IGF1R / IGF1 Receptor
Human IGF1R / IGF1 Receptor
Human (tested or 100% immunogen sequence identity)
Protein G purified
Specificity and Use
Purified human placental IGF-1 receptors.
Specific for the human IGF-1 receptor. Stimulates binding of IGF-1 and -2; stimulates basal and IGF-1 stimulated cell growth.
Research studies to delineate signal transduction pathways specific for IGF's and for detecting IGF-1 receptors in crude samples. May be used to immunoprecipitate IGF-1 receptors. Recognizes the IGF-1 a subunit on immunoblots.
PBS, pH 7.4
+4°C or -20°C, Avoid repeated freezing and thawing.
Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell.