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Anti-IGF1R / IGF1 Receptor Antibody (HRP) LS-C547152
Most Popular IGF1R / IGF1 Receptor Antibodies
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Details
| Human IGF1R / IGF1 Receptor | |
| Mouse | |
| Human, Rabbit (tested or 100% immunogen sequence identity) | |
| IgG1 Monoclonal | |
| Horseradish Peroxidase. Also available Unconjugated or conjugated with AP, APC, Biotin, FITC, PE. | |
| Protein G purified | |
| Unmodified |
Applications
- ELISA
- (applications tested for the base form of this product only)
Specificity and Use
| IGF-1R/3T3 mouse fibroblasts transfected with human type 1 IGF-receptor cDNA. | |
| Recognizes a protein of Mr=125kD, identified as the -subunit of type 1 insulin-like growth factor receptor (IGF-1R). The epitope recognized is localized between amino acid residues 283-440 (exon 4-6). Shows no cross-reactivity with insulin receptor (IR). Species Reactivity: Human. Weakly reacts with rabbit. Does not react with rat. |
Packaging
| PBS, pH 7.2. No preservative added. | |
| stable 4°C | |
| For research use only. |
About IGF1R / IGF1 Receptor
P08069
NM_000875
NP_000866.1
IGF1R Antibody, CD221 antigen Antibody, CD221 Antibody, IGF1 Receptor Antibody, IGFR Antibody, IGF-I receptor Antibody, Soluble IGF1R variant 1 Antibody, Soluble IGF1R variant 2 Antibody, Type 1 IGF receptor Antibody, IGFIR Antibody, JTK13 Antibody
Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell.
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Requested From:
Date Requested: 4/20/2018
Date Requested: 4/20/2018
