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Anti-IGF1R / IGF1 Receptor Antibody (aa514-586) LS-C24697

Ordering

Wt. Vol. Conc. Price
- 500 µl - $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular IGF1R / IGF1 Receptor Antibodies

Anti-IGF1R / IGF1 Receptor Antibody (C-Terminus) LS-C24709
Rabbit Polyclonal (IgG) to Human IGF1R / IGF1 Receptor
Human, Monkey, Mouse, Rat
IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemistry Image
Anti-IGF1R / IGF1 Receptor Antibody (clone 3C8B1) LS-C82136
Mouse Monoclonal [clone 3C8B1] (IgG2b) to Human IGF1R / IGF1 Receptor
Human
IHC - Paraffin, IHC - Frozen, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-IGF1R / IGF1 Receptor Antibody (clone 24-31, Azide-free) LS-C88320
Mouse Monoclonal [clone 24-31] (IgG1) to Human IGF1R / IGF1 Receptor
Human, Rabbit
Immunoprecipitation, ELISA
Unconjugated, Azide-free

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human IGF1R / IGF1 Receptor
Human, Pig, Rabbit
Immunoprecipitation
Unconjugated

Details

Human IGF1R / IGF1 Receptor
Mouse
Human, Pig, Rabbit (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

Immunoprecipitation

Specificity and Use

IGF1R / IGF1 Receptor antibody was raised against iGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA. Epitope: aa 514-586 (exon 7/8). Cellular Localization: Cell membrane.
aa514-586
Recognizes IGF-1 receptor a-subunit. Species cross-reactivity: human, porcine, rabbit. Does not react with rat.
Suitable for use in Immunoprecipitation and Bioassays Does not significantly inhibit IGF binding. Immunoprecipitation: 2 ug/mg protein lysate. (Use Protein G). Bioassays: Acts as a weak IGF-like agonist (Thymidine incorporation into DNA). Positive control: Placenta or breast carcinoma.

Packaging

PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About IGF1R / IGF1 Receptor

P08069 NM_000875 NP_000866.1

IGF1R Antibody, CD221 antigen Antibody, CD221 Antibody, IGF1 Receptor Antibody, IGFR Antibody, IGF-I receptor Antibody, Soluble IGF1R variant 1 Antibody, Soluble IGF1R variant 2 Antibody, Type 1 IGF receptor Antibody, IGFIR Antibody, JTK13 Antibody

Receptor tyrosine kinase which mediates actions of insulin-like growth factor 1 (IGF1). Binds IGF1 with high affinity and IGF2 and insulin (INS) with a lower affinity. The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell.

Requested From: United States
Date Requested: 12/4/2016

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