Human IGF1R / IGF1 Receptor
(tested or 100% immunogen sequence identity)
Also available conjugated with AP
Protein G purified
- (applications tested for the base form of this product only)
IGF-1R/3T3 mouse fibroblasts transfected with human type 1 IGF-receptor cDNA.
Recognizes a protein of Mr=125kD, identified as the -subunit of type 1 insulin-like growth factor receptor (IGF-1R). The epitope recognized is localized between amino acid residues 283-440 (exon 4-6). Shows no cross-reactivity with insulin receptor (IR). Species Reactivity: Human. Weakly reacts with rabbit. Does not react with rat.
This antibody acts as a weak IGF-like agonist in bioassays in which stimulation of 3H-thymidine incorporation into DNA is determined. Positive control: Placenta or breast carcinoma.
For research use only.