Chicken IFNA1 / Interferon Alpha 1

Mouse

Chicken (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

UMCh3-IFNa

Unconjugated

Protein G purified

Unmodified

Recombinant chicken Interferon alpha.

Recognizes chicken Interferon alpha (chIFN-alpha). The classification of mammalian cytokines with antiviral activity, is well documented as being either Type I Interferon (IFNI) or Type II Interferon (IFNII). This is not the case for avian IFNs however, even though IFN was first detected in the chicken. A growing number of functional studies indicate similarities between chicken IFN and mammalian IFNI, revealing the conservation of cysteine residues and the existence of around ten closely related intron-less IFN alpha genes. Further research has shown that chIFN-alpha genes are strongly expressed following viral infection of monocyte-derived macrophage and embryo fibroblasts and that recombinant chicken IFN acts as a potent antiviral agent. Does not cross react with IFN beta or IFN gamma and does not neutralize chIFN-alpha.

• Western blot
• ELISA

Western Blot: LS-C44822 detects a band of approximately 19 kD.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P01562 NCBI: NM_024013 NP_076918.1