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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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IDUA / MPS1 Antibody (aa26‑653, clone 452619) LS‑C125738
Antibody
MPS1 antibody LS-C125738 is an unconjugated mouse monoclonal antibody to human MPS1 (IDUA). Validated for ELISA and WB.
Catalog
Size
Price
LS-C125738-100
100 µg (0.5 mg/ml)
Unavailable

Popular IDUA / MPS1 Products

Antibody
Species: Human
Applications: Western blot, Immunoprecipitation, ELISA
Antibody
Species: Human
Applications: Western blot
Western blot of Human ACHN . IDUA antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Guinea pig, Horse
Applications: Western blot
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Bovine, Guinea pig, Hamster, Horse
Applications: IHC, IHC - Paraffin, Western blot

Product Description

MPS1 antibody LS-C125738 is an unconjugated mouse monoclonal antibody to human MPS1 (IDUA). Validated for ELISA and WB.
About IDUA / MPS1
IDUA / MPS1 encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I). P35475 NM_000203 NP_000194.2

IDUA Antibody, Alpha-L-iduronidase Antibody, MPS1 Antibody, Iduronidase, alpha-L- Antibody, IDA Antibody


Specifications

Target
Human IDUA / MPS1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [452619]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (1 - 2 µg/ml)
  • ELISA (0.5 - 1 µg/ml)
Immunogen
IDUA / MPS1 antibody was raised against nS0-derived, recombinant human IDUA aa26-653.
Epitope
aa26-653
Specificity
Recognizes human Alpha-L-Iduronidase. Species sequence Homology: Mouse (79%), chicken (61%).
Usage
Suitable for use in ELISA and Western Blot. Direct ELISA: 0.5-1 ug/ml. The detection limit is ~1 ng/well. Antibody was tested using full-length, recombinant protein. Western Blot: 1-2 ug/ml. Using a colorimetric detection system, the detection limit is ~5 ng/lane under non-reducing and reducing conditions. Antibody tested in WB using the full-length recombinant protein. Chemiluminescent detection will increase sensitivity by 5-50 fold.
Presentation
Lyophilized from PBS, pH 7.4, 5% trehalose
Reconstitution
200 µl Reconstitute with sterile PBS
Storage
Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/24/2018

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