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Anti-IDE Antibody (aa914-924) IHC-plus™ LS-B3954

Note: This antibody replaces LS-C55007

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml Unavailable

Related Products

37 IDE Antibodies

Most Popular IDE Antibodies

Anti-IDE Antibody (aa914-924) LS-C54995
Goat Polyclonal to Mouse IDE
Mouse, Rat, Hamster
Western blot, ELISA
Unconjugated
Western blot Image
Anti-IDE Antibody (aa914-924) IHC-plus™ LS-B3954
Goat Polyclonal to Human IDE
Human, Bat, Dog, Horse
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-IDE Antibody (aa222-233) IHC-plus™ LS-B4179
Goat Polyclonal to Human IDE
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-IDE Antibody IHC-plus™ LS-B4856
Rabbit Polyclonal to Human IDE
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-IDE Antibody (Internal, Biotin) LS-C278543
Rabbit Polyclonal (IgG) to Human IDE
Human
IHC, Western blot, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human IDE
Human, Bat, Dog, Horse
IHC - Paraffin, Western blot, ELISA
Unconjugated

Details

Human IDE
Goat
Human, Bat, Dog, Horse (tested or 100% immunogen sequence identity)
Monkey, Bovine, Pig, Rabbit, Chicken, Xenopus, Zebrafish (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (2.5 µg/ml)
  • Western blot (0.1 - 0.3 µg/ml)
  • ELISA (1:32000)

Specificity and Use

IDE antibody was raised against synthetic peptide C-QQYNFDRDNTE from an internal region of human IDE (NP_004960.1, NP_001159418.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Elephant, Panda, Dog, Bat, Horse, Opossum, Platypus (100%); Monkey, Bovine, Rabbit, Pig, Chicken, Xenopus, Zebrafish (91%); Mouse, Rat, Hamster, Sea anemone, Ant, Trichoplax (82%).
LS-E26391 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B3954. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa914-924
Human IDE. This antibody is expected to recognize both reported isoforms (NP_004960.1 and NP_001159418.1).

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About IDE

P14735 NM_004969 NP_004960.2

IDE Antibody, Abeta-degrading protease Antibody, Insulinase Antibody, INSULYSIN Antibody, Insulin protease Antibody, Insulin-degrading enzyme Antibody

IDE is a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid.

Immunohistochemistry

Immunohistochemistry
Anti-IDE antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3954 concentration 2.5 ug/ml.

Immunohistochemistry

Immunohistochemistry
Anti-IDE antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3954 concentration 2.5 ug/ml.

Western blot

Western blot
Antibody (0.1 ug/ml) staining of K562 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From: 
Date Requested: 4/23/2017

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