Products

Antibodies
All Antibodies
Primary Antibodies
Secondary Antibodies
IHC-plus Antibodies
Isotype Control Antibodies

ELISA and Assay Kits
All Kits
Assay Kits
Traditional ELISA Kits
Cell-Based ELISA Kits
DNA-Binding ELISA Kits
Phospho-Specific ELISA Kits
ELISA Development Kits
Chemiluminescent CLIA Kits

Proteins
All Proteins
Recombinant Proteins
Native Proteins
Over-expression Lysates
Cell and Tissue Lysates
Bio-active Proteins
Animal-free Proteins
Synthetic Peptides

Immunohistochemistry
Comprehensive IHC Reports
Custom IHC Services
TCR Screening Services
IHC-plus Antibodies

Services

Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Have a question? CustomerSupport@LSBio.com

Resources

Purchasing
Product Ordering Terms and Conditions
Holiday Schedule
About the LSBio Guarantee
About Our Rewards Program

Reference Material
About LSBio (LifeSpan BioSciences Inc.)
About Our 2-million Specimen Tissue Bank
About Our IHC Validation Process
About Our IHC-plus™ Immunohistochemistry Protocol
Protocols

Secure Logins
Login to Our Secure ShareFile Site
Login to Our IHC Database

Distributors

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone:	866-819-4732 (Toll Free North America) 206-374-1102 (International)

Fax:	866-206-6909 (Toll Free North America) 206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.

Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions,
rewards, and special promotions.

Login Name:
Password:

Forgot password?

Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions,
rewards, and special promotions.

Login Name*:
Email*:
Password*:
Confirm Password*:
Name:
Organization:
Role:

Fields marked with a * are required.

Wish List

View Cart

Anti-ICAM-1 / CD54 Antibody (clone 4D10) LS-C96264

Catalog	Size	Price
LS-C96264-100	100 µg	Unavailable

Related Products

388 ICAM-1 / CD54 Antibodies

Most Popular ICAM-1 / CD54 Antibodies

Anti-ICAM-1 / CD54 Antibody (clone MEM-111) IHC-plus™ LS-B1850

Antibody:	Mouse Monoclonal [clone MEM-111] (IgG2a) to Human ICAM-1 / CD54
Reactivity:	Human, Rat, Bovine
Application:	IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Format:	Unconjugated

Anti-ICAM-1 / CD54 Antibody (clone 15.2) IHC-plus™ LS-B3431

Antibody:	Mouse Monoclonal [clone 15.2] (IgG1) to Human ICAM-1 / CD54
Reactivity:	Human, Pig
Application:	IHC - Paraffin, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Format:	Unconjugated

Anti-ICAM-1 / CD54 Antibody (Biotin) LS-C123071

Antibody:	Rabbit Polyclonal to Human ICAM-1 / CD54
Reactivity:	Human, Baboon, Monkey, Cynomolgus
Application:	IHC - Frozen, Western blot, Immunoprecipitation, ELISA
Format:	Biotin Conjugated

Anti-ICAM-1 / CD54 Antibody (clone 15.2, Azide-free) LS-C134492

Antibody:	Mouse Monoclonal [clone 15.2] (IgG1,k) to Human ICAM-1 / CD54
Reactivity:	Human
Application:	Western blot, Flow Cytometry, ELISA
Format:	Unconjugated, Azide-free

Anti-ICAM-1 / CD54 Antibody (clone 8.4A6, Azide-free) LS-C134497

Antibody:	Mouse Monoclonal [clone 8.4A6] (IgG1) to Human ICAM-1 / CD54
Reactivity:	Human
Application:	Flow Cytometry, ELISA
Format:	Unconjugated, Azide-free

Antibody:	Mouse Monoclonal [clone 4D10]
Reactivity:	Human
Application:	IHC - Paraffin
Format:	Unconjugated

Details

Target:	ICAM-1 / CD54
Host:	Mouse
Reactivity:	Human (tested or 100% immunogen sequence identity)
Clonality:	Monoclonal [4D10]
Conjugations:	Unconjugated
Purification:	Affinity purified
Modifications:	Unmodified

Applications

Approved:

IHC - Paraffin (1:800)

Specificity and Use

Immunogen:

ICAM-1 / CD54 antibody was raised against cultured human endothelial cells

Specificity:

The antigen is CD54, the antibody recognizes an epitope on domain 1 of the molecule as tested on transfectants. Biochemistry: Clone 1304 stains a 95kD single chain integral membrane glycoprotein. The epitope is stable against acetone or paraformaldehyde fixation. ICAM 1 also functions as a rhinovirus receptor. Antigen distribution: Isolated cells: ICAM-1 expression can be induced on endothelial cells by in vitro stimulation with IL-1, TNF-alpha and IFN-gamma. Tissue sections: In inflamed lesions, the antibody reacts with stimulated endothelial cells, epithelial cells and fibroblasts and with haemopoietic cells such as macrophages, dendritic cells in Peyer's patches, lymph nodes and tonsils. Specificity: Human: CD54. Other: not tested.

Packaging

Presentation:	Lyophilized from PBS pH 7.2, 10mg/ml BSA, 0.01% thimerosal
Reconstitution:	0.5ml distilled water
Storage:	Store at 4°C.
Restrictions:	For research use only.

About ICAM-1 / CD54

Uniprot: P05362 NCBI: NM_000201 NP_000192.2

Synonyms: ICAM1 Antibody, BB2 Antibody, CD54 antigen Antibody, CD54 Antibody, ICAM-1 Antibody, p3.58 Antibody

Description: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.

(More About ICAM-1 / CD54)

Print This Page Email

Technical Help Review

Review This Product

Requested From:
Date Requested: 6/27/2017

Get Social With Us!

Catalog Number