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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ICAM‑1 / CD54 Antibody (clone 15.2) LS‑C134488
CD54 antibody LS-C134488 is an unconjugated mouse monoclonal antibody to human CD54 (ICAM-1). Validated for ELISA, Flow, IHC and WB.
Catalog
Size
Price
LS-C134488-100
100 µg (1 mg/ml)
Unavailable

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Flow cytometry of ICAM1 / CD54 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: Western blot, Flow Cytometry, ELISA
Flow cytometry of ICAM1 / CD54 antibody This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Human
Applications: Flow Cytometry, ELISA

Product Description

CD54 antibody LS-C134488 is an unconjugated mouse monoclonal antibody to human CD54 (ICAM-1). Validated for ELISA, Flow, IHC and WB.
About ICAM-1 / CD54
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus. P05362 NM_000201 NP_000192.2

ICAM1 Antibody, BB2 Antibody, CD54 antigen Antibody, CD54 Antibody, ICAM-1 Antibody, p3.58 Antibody


Specifications

Target
Human ICAM-1 / CD54
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [15.2]
Conjugations
Unconjugated. Also available conjugated with Biotin, FITC, RPE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot
  • Flow Cytometry
  • ELISA
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ICAM-1 / CD54 antibody was raised against human monocytes.
Specificity
D1 domain of the CD54 molecule of 90 kd.
Usage
ELISA: Capture.
Presentation
50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/ml Gentamicin sulfate
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Flow Cytometry

Flow cytometry of ICAM1 / CD54 antibody
Flow cytometry of ICAM1 / CD54 antibody

Flow Cytometry

Flow cytometry of ICAM1 / CD54 antibody
Flow cytometry of ICAM1 / CD54 antibody

Flow Cytometry

Flow cytometry of ICAM1 / CD54 antibody
Flow cytometry of ICAM1 / CD54 antibody

Flow Cytometry

Flow cytometry of ICAM1 / CD54 antibody
Flow cytometry of ICAM1 / CD54 antibody


Requested From: 
Date Requested: 6/18/2018

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