Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Western blot (1:1000 - 1:2000)
Specificity and Use
HUWE1 / ARFBP1 antibody was raised against the epitope that this antibody recognizes maps to a region between residues 2250 and 2300 of human Upstream Regulatory Element Binding Protein 1 using the numbering given in entry NP_113584.2 (GeneID 10075).
Species cross-reactivity: Cross-reacts with Human.
Suitable for use in ELISA, Western Blot and Immunoprecipitation. Western Blot: 1:1000-1:2000.
HUWE1 Antibody, ARF-binding protein 1 Antibody, ARF-BP1 Antibody, BJ-HCC-24 tumor antigen Antibody, Ib772 Antibody, KIAA0312 Antibody, LASU1 Antibody, Mcl-1 ubiquitin ligase E3 Antibody, HECTH9 Antibody, MULE Antibody, HSPC272 Antibody, KIAA1578 Antibody, URE-B1 Antibody, UREB1 Antibody, URE-binding protein 1 Antibody, HECT domain protein LASU1 Antibody, Large structure of UREB1 Antibody
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Regulates apoptosis by catalyzing the polyubiquitination and degradation of MCL1. Mediates monoubiquitination of DNA polymerase beta (POLB) at 'Lys-41', 'Lys-61' and 'Lys-81', thereby playing a role in base-excision repair. Also ubiquitinates the p53/TP53 tumor suppressor and core histones including H1, H2A, H2B, H3 and H4.