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Anti-HUPF2 / UPF2 Antibody (aa630-656) LS-C160443

Catalog Size Price
LS-C160443-400 400 µl Unavailable

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16 HUPF2 / UPF2 Antibodies

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Anti-HUPF2 / UPF2 Antibody (aa630-656) LS-C160443
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Western blot, Flow Cytometry
Western blot Image
Anti-HUPF2 / UPF2 Antibody (aa633-660) LS-C326206
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Anti-HUPF2 / UPF2 Antibody (aa1-50) IHC-plus™ LS-B14191
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100% Guaranteed Publications (1)
Rabbit Polyclonal to Human HUPF2 / UPF2
Western blot, Flow Cytometry


Human HUPF2 / UPF2
Human (tested or 100% immunogen sequence identity)
Protein A purified


  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

LS-E413 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C160443. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
This UPF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 630-656 amino acids from the Central region of human UPF2.


PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

Publications (1)

Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness. Nguyen A, Yoshida M, Goodarzi H, Tavazoie SF. Nature communications. 2016 7:11246. (WB; Human) [Full Text Article] [PubMed:27138336] [PMC:PMC4857405]

About HUPF2 / UPF2

Q9HAU5 NM_015542 NP_056357.1

UPF2 Antibody, DKFZP434D222 Antibody, KIAA1408 Antibody, RENT2 Antibody, Smg-3 Antibody, Yeast Upf2p homolog Antibody, HUPF2 Antibody

Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC). Recruited by UPF3B associated with the EJC core at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF3B stimulates both ATPase and RNA helicase activities of UPF1.

Western blot

Western blot
UPF2 Antibody western blot of MCF-7 cell line lysates (35 ug/lane). The UPF2 antibody detected the UPF2 protein (arrow).

Flow Cytometry

Flow Cytometry
UPF2 Antibody flow cytometry of MCF-7 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Requested From: 
Date Requested: 3/19/2018

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