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Anti-HTR1D / 5-HT1D Receptor Antibody (aa1-18) IHC-plus™ LS-B2041

Note: This antibody replaces LS-C612

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular HTR1D / 5-HT1D Receptor Antibodies

Anti-HTR1D / 5-HT1D Receptor Antibody (N-Terminus) IHC-plus™ LS-A588
Rabbit Polyclonal to Human HTR1D / 5-HT1D Receptor
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-HTR1D / 5-HT1D Receptor Antibody (Cytoplasmic Domain) IHC-plus™ LS-A589
Rabbit Polyclonal to Human HTR1D / 5-HT1D Receptor
Human, Pig
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-HTR1D / 5-HT1D Receptor Antibody (Extracellular Domain) IHC-plus™ LS-A590
Rabbit Polyclonal to Human HTR1D / 5-HT1D Receptor
Human, Monkey
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Rat HTR1D / 5-HT1D Receptor
Rat, Human, Mouse
IHC - Paraffin, Western blot
Unconjugated

Details

Rat HTR1D / 5-HT1D Receptor
Rabbit
Rat, Human, Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot (2 µg/ml)

Specificity and Use

HTR1D / 5-HT1D Receptor antibody was raised against synthetic peptide from rat HTR1D / 5-HT1D.
aa1-18
A mixture of synthetic peptides corresponding to amino acids 1-18 and 251-267 of rat 5-HT1DR (Genbank accession no. NP_036984).
Immunohistochemistry: LS-B2041 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2041 was determined to be 10 ug/ml.

Packaging

PBS, 0.02% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About HTR1D / 5-HT1D Receptor

P28221 NM_000864 NP_000855.1

HTR1D Antibody, 5-HT1d alpha receptor Antibody, 5HT1D Receptor Antibody, 5-HT1d-type serotonin receptor Antibody, 5-HT1D Antibody, 5-HT-1D Antibody, 5-HT-1D-alpha Antibody, 5-HT1d receptor Antibody, HT1d receptor Antibody, HTR1DA Antibody, HTRL Antibody, HT1DA Antibody, Serotonin receptor 1D Antibody, RDC4 Antibody, Gpcr14 Antibody, Serotonin 1d receptor Antibody, Serotonin 5-HT-1d receptor Antibody

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.

Immunohistochemistry

Immunohistochemistry
Anti-5HT1D Receptor antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2041 concentration 10 ug/ml.

Western blot

Western blot
Western blot of 5-HT1DR in brain lysate with anti-5-HT1DR pcAb . A protein band of approximate molecular weight of 40 kDa was detected.

Requested From: United States
Date Requested: 12/3/2016

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