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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HSP90B1 / GP96 / GRP94 Antibody (Internal) LS‑C43030
Antibody
GRP94 antibody LS-C43030 is an unconjugated rabbit polyclonal antibody to GRP94 (HSP90B1 / GP96) from human, bovine, cynomolgus monkey and other species. Validated for IF and WB.
Catalog
Size
Price
LS-C43030-100
100 µl
Unavailable

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 This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Product Description

GRP94 antibody LS-C43030 is an unconjugated rabbit polyclonal antibody to GRP94 (HSP90B1 / GP96) from human, bovine, cynomolgus monkey and other species. Validated for IF and WB.
About HSP90B1 / GP96 / GRP94
Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. P14625 NM_003299 NP_003290.1

HSP90B1 Antibody, ECGP Antibody, Endoplasmin Antibody, gp96 homolog Antibody, gp96 Antibody, GRP-94 Antibody, GRP94 Antibody, Tumor rejection antigen 1 Antibody, TRA1 Antibody


Specifications

Target
Human HSP90B1 / GP96 / GRP94
Host
Rabbit
Reactivity
Human, Bovine, Pig, Sheep, Cynomolgus monkey (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Modifications
Unmodified
Applications
  • Immunofluorescence
  • Western blot (1:1000)
Immunogen
Synthetic peptide derived from the internal sequence of human GRP94 conjugated to KLH.
Epitope
Internal
Specificity
Recognizes the 94 kD glucose regulated protein, GRP94, also known as tumor rejection antigen (gp96). GRP94 is an endoplasmic reticulum resident molecular chaperone, a paralog of cytoplasmic Hsp90. GRP94 assists in the folding of membrane-bound proteins including the Toll-like receptors, certain subclasses of integrins and some secreted proteins such as IgG. Detects a band of ~105 kD in cynomolgus monkey brain lysates by western blotting.
Presentation
Serum, 0.09% sodium azide.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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