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In mammalian cells, there are two or more genes encoding cytosolic Hsp90 homologues, with the human Hsp90 alpha showing 85% sequence identity to Hsp90 beta. The alpha- and the beta-forms are thought to be the result of a gene duplication event that occurred millions of years ago. HSP90 Beta is encoded by the HSP90B1 gene and is located in the endoplasmic reticulum.
Target Name: | HSP90 Beta |
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