Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway.
IHC of paraffin-embedded H520 xenograft using Histamine H2 Receptor antibody at 1:100 dilution.
Immunofluorescence of methanol-fixed HeLa using Histamine H2 Receptor antibody at 1:200 dilution.
Histamine H2 Receptor antibody [N1], N-term detects HRH2 protein by Western blot analysis. A. 30 ug U87-MG whole cell lysate/extract. B. 30 ug SK-N-SH whole cell lysate/extract. 10 % SDS-PAGE. Histamine H2 Receptor antibody [N1], N-term dilution:1:1000
Requested From: United States
Date Requested: 1/24/2017