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Anti-HPV18 E7 Antibody (clone 718-238) LS-C58371


Wt. Vol. Conc. Price
200 µg - - Unavailable

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100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 718-238] (IgG2b) to Human Papillomavirus HPV18 E7
Human Papillomavirus
Western blot, ELISA


Human Papillomavirus HPV18 E7
Human Papillomavirus (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [718-238]
Affinity purified


  • Western blot

Specificity and Use

HPV18 E7 antibody was raised against oncoprotein E7 from human papillomavirus 18.
Recognizes the E7 oncoprotein of human papilloma virus 18. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. May be used to detect the E7 protein of HPV-16 in ELISA assays. Does not cross-react with the E7 protein of HPV-16.
ELISA: This product may be used in an indirect ELISA or as a detection antibody in a sandwich ELISA together with LS-C58370 as a capture reagent.


PBS, pH 7.2, 0.09% sodium azide.
Long term: -20°C; Short term: -20°C
For research use only.

About HPV18 E7

Requested From: 
Date Requested: 4/26/2017

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