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HOXC13 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the development of hair, nail, and filiform papilla.
Gene Name: | homeobox C13 |
Synonyms: | HOXC13, Homeo box C13, Homeobox protein Hox-3G, Homeobox protein Hox-C13, Homeo box 3G, HOX3G, ECTD9, Homeobox C13, HOX3, NUP98/HOXC13 |
Target Sequences: | NM_017410 NP_059106.2 P31276 |
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