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HOXB9 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.
Gene Name: | homeobox B9 |
Synonyms: | HOXB9, Homeobox B9, HOX-2.5, Homeo box 2E, Homeobox protein Hox-B9, HOX2E, Homeobox protein Hox-2E, Homeo box B9, Homeobox protein Hox-2.5, HOX2 |
Target Sequences: | NM_024017 NP_076922.1 P17482 |
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