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Anti-TCF7 Antibody (N-Terminus) LS-C152705

Catalog Size Price
LS-C152705-100 100 µg (0.84 mg/ml) Unavailable

Related Products

52 TCF7 Antibodies

Most Popular TCF7 Antibodies

Anti-TCF7 Antibody (aa228-277) IHC-plus™ LS-B1003
Rabbit Polyclonal to Human TCF7
Human, Monkey, Bat, Bovine, Guinea pig, Horse, Rabbit
IHC, IHC - Paraffin, Western blot
Unconjugated
Anti-TCF7 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1003 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-TCF7 Antibody (aa102-269) LS-C39560
Mouse Monoclonal (IgG1) to Human TCF7
Human
IHC, ICC, Western blot, ELISA
Unconjugated
Anti-TCF7 Antibody (Leu158) LS-C39561
Rabbit Monoclonal (IgG) to Human TCF7
Human, Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated
Anti-TCF7 Antibody (Pro95) LS-C39562
Rabbit Monoclonal (IgG) to Human TCF7
Human, Mouse
IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-TCF7 Antibody (N-Terminus) LS-C352911
Rabbit Polyclonal to Human TCF7
Human, Bovine
IHC, IHC - Paraffin, Western blot, Immunoprecipitation
Unconjugated
Immunohistochemical analysis of TCF7 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.

100% Guaranteed
Mouse Monoclonal (IgG) to Human TCF7
Human
IHC, ICC, Western blot
Unconjugated

Details

Human TCF7
Mouse
Human (tested or 100% immunogen sequence identity)
IgG Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • IHC
  • ICC
  • Western blot

Specificity and Use

TCF7 antibody was raised against maltose binding protein (MBP) fusion protein corresponding to residues 102-269 of human TCF-1A splice variant. The epitope maps to a region just N-terminal to the High Mobility Group (HMG) box
N-Terminus
Recognizes multiple splice isoforms of TCF-1. The epitope maps to a region just N-terminal to the High Mobility Group (HMG) box.

Packaging

0.2 M Tris-glycine, pH 7.5, 0.15 M sodium chloride, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze-thaw cycles. Store undiluted.
For research use only.

About TCF7

P36402 NM_003202 NP_003193.2

TCF7 Antibody, TCF-7 Antibody, TCF1 Antibody, Transcription factor 7 Antibody, T-cell factor 1 Antibody, TCF-1 Antibody

Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.

Western blot

1 µg/mL of this antibody detected TCF-1 on 10 µg of Jurkat cell lysate.
1 µg/mL of this antibody detected TCF-1 on 10 µg of Jurkat cell lysate.

Requested From: 
Date Requested: 5/23/2018

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