Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone EP-4] (IgM,k) to Human HLA-B27
Human (tested or 100% immunogen sequence identity)
IgM,k Monoclonal [EP-4]
Specificity and Use
HLA-B27 antibody was raised against lymphocytes from HLA-B27 individual.
EP-4 recognizes the HLA-B27 cell surface antigen on human cells. Since EP-4 recognizes the HLA-B27 antigen, it may be used to HLA type human lymphoctyes. Approximately 60% of patients with ankylosing spondylitis are HLA-B27 positive. This reagent can be used to help identify this HLA haplotype in human lymphocytes. Monoclonal antibody EP-4 recognizes the HLA-B27 antigen expressed on individuals with this HLA haplotype.
PBS, 0.05% sodium azide
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.