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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Histone H1 Antibody LS‑C24253
Antibody
Histone H1 antibody LS-C24253 is an unconjugated mouse monoclonal antibody to human Histone H1. Validated for IF, IHC and WB.
Catalog
Size
Price
LS-C24253-500
500 µl
Unavailable

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Product Description

Histone H1 antibody LS-C24253 is an unconjugated mouse monoclonal antibody to human Histone H1. Validated for IF, IHC and WB.
About Histone H1
Histone H1 is one of the five main histone protein families which are components of chromatin in eukaryotic cells. Though highly conserved, it is nevertheless the most variable histone in sequence across species. Metazoan H1 proteins feature a central globular domain and long C- and short N-terminal tails. H1 is involved with the packing of the "beads on a string" sub-structures into a high order structure, whose details have not yet been solved.

Specifications

Target
Human Histone H1
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Immunofluorescence
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Histone H1 antibody was raised against nuclei of myeloid leukemia biopsy cells. Cellular Localization: Nuclear.
Specificity
Recognizes human histone H1. Molecular Weights of Histones: Lysine Rich (H1, f1): ~21500 Slightly Lysine Rich (H2a, f2a2): 14004 Slightly Lysine Rich (H2b, f2b): 13774 Arginine Rich (H3, f3): 15324 Arginine Rich (H4, f2a1): 11282.
Usage
Suitable for use in Immunofluorescence and Immunohistochemistry. Not suitable for use in Western Blot. Immunohistochemistry (formalin/paraffin): 2-4 ug/ml. No special pretreatment is required for staining of formalin-fixed, paraffin-embedded tissues. Positive control: Tonsil or lymph node.
Presentation
PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/17/2018

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