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Plays an essential role in normal development and survival. Involved in regulation of the expansion or survival of lymphoid cells. Required for de novo or maintenance DNA methylation. May control silencing of the imprinted CDKN1C gene through DNA methylation. May play a role in formation and organization of heterochromatin, implying a functional role in the regulation of transcription and mitosis.
Gene Name: | helicase, lymphoid-specific |
Synonyms: | HELLS, Lymphoid-specific helicase, LSH, Nbla10143, SMARCA6, Helicase, lymphoid-specific, PASG |
Target Sequences: | NM_018063 NP_060533.2 Q9NRZ9 |
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