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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Heat Shock Protein 70 / HSPA1A Antibody (aa436‑503) LS‑C24171
Antibody
HSPA1A antibody LS-C24171 is an unconjugated mouse monoclonal antibody to HSPA1A (Heat Shock Protein 70) from human, mouse, rat and other species. Validated for WB. Cited in 1 publication.
Catalog
Size
Price
LS-C24171-50
50 µg (1 mg/ml)
Unavailable
LS-C24171-200
200 µg
Unavailable

Popular Heat Shock Protein 70 / HSPA1A Products

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Applications: Western blot, Immunoprecipitation
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Applications: ICC, Immunofluorescence, Western blot, ELISA

Product Description

HSPA1A antibody LS-C24171 is an unconjugated mouse monoclonal antibody to HSPA1A (Heat Shock Protein 70) from human, mouse, rat and other species. Validated for WB. Cited in 1 publication.
About Heat Shock Protein 70 / HSPA1A
In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins.

Specifications

Target
Human Heat Shock Protein 70 / HSPA1A
Host
Mouse
Reactivity
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Pig, Rabbit, Sheep, Chicken, Drosophila, C. elegans (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • Western blot (1 µg/ml)
Immunogen
Purified Hsp70 isolated from human HeLa cells.
Epitope
aa436-503
Specificity
Recognizes human Hsp70 protein at ~70kD, corresponding to the apparent MW of the inducible Hsp70. Epitope: aa436-503. Does not cross-react with the constitutive Hsc70 (Hsp73). Species cross-reactivity: mouse, rat, beluga, bovine, C. elegans, canine, chicken, Drosophila, fish (carp), guinea pig, hamster, monkey, porcine, rabbit, sheep, teal.
Usage
Suitable for use in Western Blot. Western Blot (Colorimetric): 1:1000. Positive control: Recombinant Human Hsp70 Protein.
Presentation
PBS, pH 7.2, 50% glycerol, 0.01% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Down-regulating cold shock protein genes impairs cancer cell survival and enhances chemosensitivity. Zeng Y, Kulkarni P, Inoue T, Getzenberg RH. Journal of cellular biochemistry. 2009 May;107:179-88. [Full Text Article] [PubMed:19277990]

Customer Reviews (0)


Requested From: 
Date Requested: 6/17/2018

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