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Anti-HCN1 Antibody LS-C15642


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $405
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular HCN1 Antibodies

Anti-HCN1 Antibody (N-Terminus) LS-C7338
Rabbit Polyclonal (IgG) to Human HCN1
Human, Mouse
Western blot, ELISA
Anti-HCN1 Antibody LS-C15642
Rabbit Polyclonal (IgG) to Human HCN1
Human, Mouse, Rat, Rabbit
Western blot, ELISA
Anti-HCN1 Antibody (aa778-910, clone S70-28) IHC-plus™ LS-B6436
Mouse Monoclonal [clone S70-28] (IgG1) to Rat HCN1
Rat, Human, Mouse
IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human HCN1
Human, Mouse, Rat, Rabbit
Western blot, ELISA


Human HCN1
Human, Mouse, Rat, Rabbit (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • Western blot (1 - 10 µg/ml)
  • ELISA (1:10000 - 1:100000)

Specificity and Use

HCN1 antibody was raised against a 23-aa peptide sequence corresponding to the pore region of human HCN1 corresponding to amino acids 346-368.
The pore region of HCN1 (HCNP15-P) is very conserved among various HCNs. HCN1: mouse, rat, human, rabbit=100%; HCN2: mouse, rat, human (86%); HCN3: mouse (95%), rat (90%); HCN4: rat, human (95%). The HCNP15-P sequence is also conserved in insect (Helothis virescens, 78%), Drosophila (78%) and Sea urchin (S. purpuratus, 69%) HCNs. Therefore, antibodies to HCNP15-P should react with most HCNs and related sequences. Antibody reactivity in various species is not known. The HCNP15-P control peptide, because of its low MW (<3kD), is not suitable for Western. It should be used for ELISA or antibody blocking experiments (use 5-10 ug control peptide per 1 ug of aff pure IgG or 1 ul antiserum) to confirm antibody specificity. This antibody may be useful in studying various HCNs and to examine the possibility of immunoblocking the pore region and impact on the functionality of HCNs proteins.
Suitable for use in ELISA, Western Blot. Western Blot: 1:1000-1:5000 for neat serum and 1-10 ug/ml for affinity pure using ECL. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well.


PBS, pH 7.4, 0.1% BSA.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
For research use only.

About HCN1

O60741 NM_021072 AAC39759.1

HCN1 Antibody, BCNG1 Antibody, BCNG-1 Antibody, HAC2 Antibody, HAC-2 Antibody

Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih). May mediate responses to sour stimuli.

Requested From: United States
Date Requested: 10/21/2016

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