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Anti-HCAR3 / GPR109B / HM74 Antibody (aa1-50) IHC-plus™ LS-B1781

Note: This antibody replaces LS-C47293

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular HCAR3 / GPR109B / HM74 Antibodies

Anti-HCAR3 / GPR109B / HM74 Antibody (N-Terminus) IHC-plus™ LS-A179
Rabbit Polyclonal to Human HCAR3 / GPR109B / HM74
Human
IHC - Paraffin, ICC
Unconjugated
Immunohistochemistry Image
Anti-HCAR3 / GPR109B / HM74 Antibody (aa71-99, APC) LS-C257956
Rabbit Polyclonal (IgG) to Human HCAR3 / GPR109B / HM74
Human
Western blot, ELISA
APC Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human HCAR3 / GPR109B / HM74
Human, Dog, Hamster
IHC - Paraffin, Western blot
Unconjugated

Details

Human HCAR3 / GPR109B / HM74
Rabbit
Human, Dog, Hamster (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot (0.5 - 2 µg/ml)

Specificity and Use

HCAR3 / GPR109B / HM74 antibody was raised against a portion of amino acids 1-50of human GPR109B.
aa1-50
A portion of amino acids 1-50 of human GPR109B.
Immunohistochemistry: LS-B1781 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1781 was determined to be 10 ug/ml.

Packaging

PBS, 0.2% gelatin, 0.05% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
For research use only.

About HCAR3 / GPR109B / HM74

P49019 NM_006018 NP_006009.2

HCAR3 Antibody, GPR109B Antibody, GTP-binding protein Antibody, NIACR2 Antibody, HM74 Antibody, HM74b Antibody, Nicotinic acid receptor 2 Antibody, Putative chemokine receptor Antibody, Niacin receptor 2 Antibody, Puma-g Antibody, HCA3 Antibody, PUMAG Antibody

Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.

Immunohistochemistry

Immunohistochemistry
Anti-GPR109B / HM74 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1781 concentration 10 ug/ml.

Western blot

Western blot
Western blot of human GPR109B in human liver lysate using antibody at 1 ug/ml.

Requested From: United States
Date Requested: 12/9/2016

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