Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal (IgG1) to Human GYPC / Glycophorin C
Western blot, Flow Cytometry
Human GYPC / Glycophorin C
Human (tested or 100% immunogen sequence identity)
Protein G purified
Specificity and Use
GYPC / Glycophorin C antibody was raised against human erythrocytes.
Recognizes an epitope in the N-terminal region of glycophorin C (GPC). Glycophorin C is an integral membrane protein which carries the Gerbich blood group antigens. Expression of GPC is not restricted to erythroid cells but is broadly distributed in both erythroid and non-erythroid tissues.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
Tris buffered glycine, pH 7.4, 0.09% sodium azide.
Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene.