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Anti-GYPC / Glycophorin C Antibody (aa112-128) LS-C14406

Ordering

Wt. Vol. Conc. Price
200 µg - - $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Mouse Monoclonal (IgG1) to Human GYPC / Glycophorin C
Human
IHC - Frozen, Western blot, Immunoprecipitation
Unconjugated

Details

Human GYPC / Glycophorin C
Mouse
Human (tested or 100% immunogen sequence identity)
Monkey, Bat (at least 90% immunogen sequence identity)
IgG1 Monoclonal
Purified

Applications

IHC - Frozen, Western blot, Immunoprecipitation

Specificity and Use

GYPC / Glycophorin C antibody was raised against synthetic peptide corresponding to amino acids in the cytoplasmic domain of Glycophorin C, GpC. Sequence is aa112-128 (DPALQDAGDSSRKEYFI). Percent identity by BLAST analysis: Human, Gorilla, Marmoset (100%); Monkey, Bat (94%); Mouse, Rat, Hamster, Elephant (88%); Dog, Rabbit, Pig, Platypus, Salmon, Zebrafish (82%).
aa112-128
Recognizes a 17 amino acid residue within the cytoplasmic domain of glycophorin C (GPC), which has recently been designated CD236.
Immunohistochemistry (frozen). Immunoprecipitation. Western Blot. Recommended Secondary Reagents: F (ab')2 rabbit anti-mouse IgG HRP. Fusion Partners: Spleen cells from immunized Balb/c mice were fused with cells of the myeloma cell line. Recommended Negative Controls: Mouse IgG1 Negative Control.

Packaging

Tris buffered glycine, pH 7.4, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About GYPC / Glycophorin C

P04921 NM_002101 NP_002092.1

GYPC Antibody, CD236 Antibody, CD236 antigen Antibody, GLPC Antibody, Glycophorin-C Antibody, Glycoconnectin Antibody, Glycophorin C Antibody, GPC Antibody, GYPD Antibody, Sialoglycoprotein D Antibody, PAS-2 Antibody, CD236R Antibody, GE Antibody, Glycophorin-D Antibody, Glycoprotein beta Antibody, GPD Antibody, PAS-2' Antibody

Glycophorin C (GYPC) is an integral membrane glycoprotein. It is a minor species carried by human erythrocytes, but plays an important role in regulating the mechanical stability of red cells. A number of glycophorin C mutations have been described. The Gerbich and Yus phenotypes are due to deletion of exon 3 and 2, respectively. The Webb and Duch antigens, also known as glycophorin D, result from single point mutations of the glycophorin C gene.

Requested From: United States
Date Requested: 9/26/2016

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