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Anti-GRM5 / MGLUR5 Antibody LS-C149996

Ordering

Wt. Vol. Conc. Price
100 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GRM5 / MGLUR5 Antibodies

Anti-GRM5 / MGLUR5 Antibody (N-Terminus) IHC-plus™ LS-A883
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Chicken
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-GRM5 / MGLUR5 Antibody (C-Terminus) IHC-plus™ LS-A885
Rabbit Polyclonal to Human GRM5 / MGLUR5
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-GRM5 / MGLUR5 Antibody (aa19-509) LS-C72508
Mouse Monoclonal (IgG1) to Human GRM5 / MGLUR5
Human
Western blot, Flow Cytometry, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Sheep Polyclonal (IgG) to Human GRM5 / MGLUR5
Human
IHC, Western blot, ELISA
Unconjugated

Details

Human GRM5 / MGLUR5
Sheep
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA (0.5 - 1 µg/ml)

Specificity and Use

GRM5 / MGLUR5 antibody was raised against nS0-derived rhmGluR5 (aa 19 - 509).
Human mGluR5.
Western blot-This antibody can be used at 0.1-0.2 µg/ml with the appropriate secondary reagents to detect human mGluR5. The detection limit for rhmGluR5 is approximately 10 ng/lane and 1 ng/lane under non-reducing and reducing conditions, respectively. Immunohistochemistry-This antibody will detect human mGluR5 in cells and tissues. The working dilution is 2-5 µg/ml. Direct ELISA-This antibody can be used at 0.5-1.0 µg/ml with the appropriate secondary reagents to detect human mGluR5. The detection limit for rhmGluR5 is approximately 0.2 ng/well. In this format, this antibody shows approximately. 20% cross-reactivity with rhmGluR1 and less than 5% cross-reactivity with rhmGluR2 and rhmGluR3.

Packaging

Lyophilized from 0.2 µm filtered 100 mM NaHCO3, pH 8.3, 500 mM NaCl, 1% sucrose.
Store at -20°C.
For research use only.

About GRM5 / MGLUR5

P41594 NM_000842 NP_000833.1

GRM5 Antibody, GPRC1E Antibody, MGLUR5 Antibody, Mglur5b Antibody, MGlu5 Antibody

Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain.

Requested From: United States
Date Requested: 12/3/2016

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