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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GRIA4 / GLUR4 Antibody (phospho‑Ser862) LS‑C199002
GLUR4 antibody LS-C199002 is an unconjugated rabbit polyclonal antibody to GLUR4 (GRIA4) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB.
Catalog
Size
Price
LS-C199002-50
50 µl
Unavailable
LS-C199002-100
100 µl
Unavailable

Popular GRIA4 / GLUR4 Products

Antibody
Species: Rat, Mouse
Applications: IHC, IHC - Frozen, Western blot
Anti-GRIA4 / GLUR4 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3606 concentration 5 ug/ml.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Horse, Rabbit, Chicken
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
GRIA4 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
GRIA4 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Human, Mouse
Applications: IHC, Western blot, ELISA

Product Description

GLUR4 antibody LS-C199002 is an unconjugated rabbit polyclonal antibody to GLUR4 (GRIA4) from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB.
About GRIA4 / GLUR4
Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. P48058 NM_000829 NP_000820.3

GRIA4 Antibody, GluA4 Antibody, GluR-4 Antibody, GLUR4 Antibody, GLUR4C Antibody, Glutamate receptor type d Antibody, GluR-D Antibody, GLURD Antibody, Glutamate receptor 4 Antibody


Specifications

Target
Human GRIA4 / GLUR4
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:5000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GRIA4 / GLUR4 antibody was raised against synthetic peptide derived from human GluR4 around the phosphorylation site of Ser862.
Epitope
pSer862
Specificity
GluR4 (Phospho-Ser862) Antibody detects endogenous levels of GluR4 only when phosphorylated at serine862.
Presentation
PBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The sample on the right was incubated with synthetic peptide.
IHC of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The sample on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right was incubated with synthetic peptide.

Immunohistochemistry

IHC of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The sample on the right was incubated with synthetic peptide.
IHC of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The sample on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right was incubated with synthetic peptide.

Immunohistochemistry

IHC of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The sample on the right was incubated with synthetic peptide.
IHC of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The sample on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right was incubated with synthetic peptide.

Immunohistochemistry

IHC of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The sample on the right was incubated with synthetic peptide.
IHC of paraffin-embedded human brain, using GluR4 (Phospho-Ser862) Antibody. The sample on the right was incubated with synthetic peptide.

Western blot

Western blot of extracts from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right was incubated with synthetic peptide.
Western blot of extracts from HepG2 cells treated with Forskolin 40nM 30', using GluR4 (Phospho-Ser862) Antibody. The lane on the right was incubated with synthetic peptide.


Requested From: 
Date Requested: 6/20/2018

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