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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GRIA1 / GLUR1 Antibody (C‑Terminus) LS‑C123612
Antibody
GLUR1 antibody LS-C123612 is an unconjugated rabbit polyclonal antibody to rat GLUR1 (GRIA1). Validated for IHC and WB.
Catalog
Size
Price
LS-C123612-100
100 µl
Unavailable

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Product Description

GLUR1 antibody LS-C123612 is an unconjugated rabbit polyclonal antibody to rat GLUR1 (GRIA1). Validated for IHC and WB.
About GRIA1 / GLUR1
Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. P42261 NM_000827 NP_000818.2

GRIA1 Antibody, AMPA 1 Antibody, GluR-K1 Antibody, HBGR1 Antibody, GLUH1 Antibody, GLUR1 Antibody, GLURA Antibody, Glutamate receptor 1 Antibody, GluR-A Antibody, GluA1 Antibody, GluR-1 Antibody


Specifications

Target
Rat GRIA1 / GLUR1
Host
Rabbit
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen (1:500)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GRIA1 / GLUR1 antibody was raised against peptide from the C-terminal region of rat mGluR1a.
Epitope
C-Terminus
Specificity
Recognizes rat metabotropic glutamate receptor 1a at ~125kD (monomer) and 250kD (dimer) in HEK293 cells.
Usage
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:1000. Immunohistochemistry (frozen):1:500.
Presentation
10 mM HEPES, pH 7.5, 150 mM sodium chloride, 0.09% sodium azide, 0.01% BSA, 50% glycerol
Storage
May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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