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Anti-GREM1 / Gremlin-1 Antibody (aa25-184) LS-C150203


Wt. Vol. Conc. Price
100 µg - - Unavailable

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100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Mouse GREM1 / Gremlin-1
IHC, Western blot, ELISA


Mouse GREM1 / Gremlin-1
Mouse (tested or 100% immunogen sequence identity)
IgG Polyclonal
Immunoaffinity purified


  • IHC (5 - 15 µg/ml)
  • Western blot (0.1 µg/ml)
  • ELISA (3 µg/ml)

Specificity and Use

GREM1 / Gremlin-1 antibody was raised against mouse myeloma cell line NS0-derived recombinant mouse Gremlin Lys25-Asp184 Accession # O70326.
Detects mouse Gremlin in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant human.
Western Blot, 0.1 µg/ml, Recombinant Mouse Gremlin. Immunohistochemistry, 5-15 µg/ml, Blockade of Receptor-ligand Interaction, In a functional ELISA, 1-3 µg/ml of this antibody will block 50% of the binding of 100 ng/ml of Recombinant. Human BMP-4 to immobilized Recombinant Mouse Gremlin coated at 5 µg/ml (100 ul/well).


Lyophilized from 0.2 um filtered solution in PBS, trehalose
Sterile PBS. Resuspend to 500 ul
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About GREM1 / Gremlin-1

O60565 NM_013372 NP_037504.1

GREM1 Antibody, CKTSF1B1 Antibody, DAN domain family member 2 Antibody, DAND2 Antibody, DRM Antibody, GREMLIN Antibody, Gremlin 1-like protein Antibody, Increased in high glucose-2 Antibody, Gremlin-1 Antibody, PIG2 Antibody, Proliferation-inducing gene 2 Antibody, Gremlin 1 Antibody, IHG-2 Antibody

GREM1 / Gremlin-1 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins.


Gremlin in Embryonic Mouse Ribs. Gremlin was detected in immersion fixed frozen sections of embryonic mouse ribs (15 d. p. c.) using 15 ug/ml Goat Anti-Mouse Gremlin Antigen Affinity-purified Polyclonal Antibody overnight at 4°C. Tissue was stained with Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue).

Requested From: 
Date Requested: 4/24/2017

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