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Anti-GREM1 / Gremlin-1 Antibody (aa162-176) IHC-plus™ LS-B810

Note: This antibody replaces LS-C3019


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395

LSBio (Direct) LSBio (Direct)

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Rabbit Polyclonal to Human GREM1 / Gremlin-1
IHC - Paraffin, ELISA


Human GREM1 / Gremlin-1
Human (tested or 100% immunogen sequence identity)
Protein G purified


IHC - Paraffin (10 µg/ml), ELISA (1:1000)

Specificity and Use

GREM1 / Gremlin-1 antibody was raised against synthetic peptide from human GREM1 / Gremlin 1.
Amino acids 162 to 176 of human GREM1
Immunohistochemistry: LS-B810 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B810 was determined to be 10 ug/ml.


PBS, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About GREM1 / Gremlin-1

O60565 NM_013372 NP_037504.1

GREM1 Antibody, CKTSF1B1 Antibody, DAN domain family member 2 Antibody, DAND2 Antibody, DRM Antibody, GREMLIN Antibody, Gremlin 1-like protein Antibody, Increased in high glucose-2 Antibody, Gremlin-1 Antibody, PIG2 Antibody, Proliferation-inducing gene 2 Antibody, Gremlin 1 Antibody, IHG-2 Antibody

GREM1 / Gremlin-1 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins.


Anti-Gremlin-1 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B810 concentration 10 ug/ml.

Requested From: United States
Date Requested: 11/27/2015

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