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Anti-GPR132 / G2A Antibody (Extracellular Domain) IHC-plus™ LS-A3702

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Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
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100% Guaranteed 100% Guaranteed In Stock In Stock Publications Publications (1)
Rabbit Polyclonal to Human GPR132 / G2A
Human
IHC - Paraffin
Unconjugated

Details

Human GPR132 / G2A
Rabbit
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Immunoaffinity purified

Applications

IHC - Paraffin (3 - 28 µg/ml)

Specificity and Use

GPR132 / G2A antibody was raised against synthetic 18 amino acid peptide from 3rd extracellular domain of human GPR132 / G2A. Percent identity with other species by BLAST analysis: Human, Gibbon (100%); Gorilla, Monkey (94%); Marmoset (83%).
LS-E28798 - Liquid - 50 µg - $145.00
Extracellular Domain
Human GPR132 / G2A. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PRDM4 (61%).

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze thaw cycles.
For research use only.

Publications (1)

1
Activated microglia in ischemic stroke penumbra upregulate MCP-1 and CCR2 expression in response to lysophosphatidylcholine derived from adjacent neurons and astrocytes. Kato Y, Kitagawa K, Uchiyama S, Shibata N. Neuropathology : official journal of the Japanese Society of Neuropathology. Dec; [Full Text Article] [PubMed:25443158]

About GPR132 / G2A

Q9UNW8 NM_013345 NP_037477.1

GPR132 Antibody, G2A Antibody, G protein-coupled receptor 132 Antibody, G protein-coupled receptor G2A Antibody, G2 accumulation protein Antibody, G2a receptor Antibody

May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9-hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation.

Immunohistochemistry

Immunohistochemistry
Anti-GPR132 / G2A antibody LS-A3702 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
 

Requested From: United States
Date Requested: 10/1/2016

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