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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GMPS / GMP Synthase Antibody (clone 1D10) IHC‑plus™ LS‑B4476 Best Seller
Note: This antibody replaces LS-C105074
GMP Synthase antibody LS-B4476 is an unconjugated mouse monoclonal antibody to human GMP Synthase (GMPS). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B4476-50
50 µg (0.48 mg/ml)
Unavailable

Popular GMPS / GMP Synthase Products

Formalin-fixed and paraffin-embedded kidney tissue reacted with GMPS Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Formalin-fixed and paraffin-embedded kidney tissue reacted with GMPS Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
Western blot analysis of extracts of various cell lines.
Species: Human, Mouse, Rat
Applications: IHC, Western blot
Immunohistochemistry of paraffin-embedded human small intestine at dilution 1:100
Species: Human
Applications: IHC, Western blot, ELISA

Product Description

GMP Synthase antibody LS-B4476 is an unconjugated mouse monoclonal antibody to human GMP Synthase (GMPS). Validated for ELISA, IHC and WB. Tested on 20 paraffin-embedded human tissues.
About GMPS / GMP Synthase
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP. P49915 NM_003875 NP_003866.1

GMPS Antibody, GMP synthetase Antibody, Glutamine amidotransferase Antibody, GMP synthase Antibody, MLL/GMPS fusion protein Antibody


Specifications

Target
Human GMPS / GMP Synthase
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal [1D10]
Conjugations
Unconjugated
Purification
Purified from ascites by Protein A
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (5 µg/ml)
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GMPS (NP_003866, 108 a.a. ~ 216 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Usage
Western blot performed with the recombinant protein used as the immunogen as the protein source. Sandwich ELISA (Recombinant protein).
Presentation
PBS, pH 7.4.
Storage
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

Anti-GMPS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.
Anti-GMPS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.

Immunohistochemistry

Anti-GMPS antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.
Anti-GMPS antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged GMPS is approximately 0.1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged GMPS is approximately 0.1 ng/ml as a capture antibody.

Immunohistochemistry

Anti-GMPS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.
Anti-GMPS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.

Immunohistochemistry

Anti-GMPS antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.
Anti-GMPS antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged GMPS is approximately 0.1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged GMPS is approximately 0.1 ng/ml as a capture antibody.

Immunohistochemistry

Anti-GMPS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.
Anti-GMPS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.

Immunohistochemistry

Anti-GMPS antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.
Anti-GMPS antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged GMPS is approximately 0.1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged GMPS is approximately 0.1 ng/ml as a capture antibody.

Immunohistochemistry

Anti-GMPS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.
Anti-GMPS antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.

Immunohistochemistry

Anti-GMPS antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.
Anti-GMPS antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4476 concentration 5 ug/ml.

Enzyme-Linked Immunosorbent Assay

Detection limit for recombinant GST tagged GMPS is approximately 0.1 ng/ml as a capture antibody.
Detection limit for recombinant GST tagged GMPS is approximately 0.1 ng/ml as a capture antibody.


Requested From: 
Date Requested: 6/20/2018

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