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GMPPB is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene Name: | GDP-mannose pyrophosphorylase B |
Synonyms: | GMPPB, KIAA1851 |
Target Sequences: | NM_013334 NP_037466.2 Q9Y5P6 |
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