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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GLCNE / GNE Antibody (aa169‑197) LS‑C166561 Best Seller
GNE antibody LS-C166561 is an unconjugated rabbit polyclonal antibody to human GNE (GLCNE). Validated for IHC and WB.
Catalog
Size
Price
LS-C166561-400
400 µl
Unavailable

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Product Description

GNE antibody LS-C166561 is an unconjugated rabbit polyclonal antibody to human GNE (GLCNE). Validated for IHC and WB.
About GLCNE / GNE
GLCNE / GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate-limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction. Q9Y223 NM_005476 NP_005467.1

GNE Antibody, DMRV Antibody, IBM2 Antibody, GLCNE Antibody, N-acylmannosamine kinase Antibody, NM Antibody, Uae1 Antibody


Specifications

Target
Human GLCNE / GNE
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Mouse, Rat, Hamster (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Blocking Peptide
LS-E1547 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C166561. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa169-197
Specificity
This GNE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the N-terminal region of human GNE.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

GNE Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
GNE Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

GNE Antibody western blot of human placenta tissue lysates (35 ug/lane). The GNE antibody detected the GNE protein (arrow).
GNE Antibody western blot of human placenta tissue lysates (35 ug/lane). The GNE antibody detected the GNE protein (arrow).

Immunohistochemistry

GNE Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
GNE Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

GNE Antibody western blot of human placenta tissue lysates (35 ug/lane). The GNE antibody detected the GNE protein (arrow).
GNE Antibody western blot of human placenta tissue lysates (35 ug/lane). The GNE antibody detected the GNE protein (arrow).

Immunohistochemistry

GNE Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
GNE Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

GNE Antibody western blot of human placenta tissue lysates (35 ug/lane). The GNE antibody detected the GNE protein (arrow).
GNE Antibody western blot of human placenta tissue lysates (35 ug/lane). The GNE antibody detected the GNE protein (arrow).

Immunohistochemistry

GNE Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
GNE Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Western blot

GNE Antibody western blot of human placenta tissue lysates (35 ug/lane). The GNE antibody detected the GNE protein (arrow).
GNE Antibody western blot of human placenta tissue lysates (35 ug/lane). The GNE antibody detected the GNE protein (arrow).


Requested From: 
Date Requested: 6/23/2018

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