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Anti-GFRA2 Antibody LS-C149958

Ordering

Wt. Vol. Conc. Price
100 µg 1000 µl 0.1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular GFRA2 Antibodies

Anti-GFRA2 Antibody LS-C149958
Goat Polyclonal (IgG) to Human GFRA2
Human
IHC, Western blot, ELISA
Unconjugated
Anti-GFRA2 Antibody LS-C150113
Goat Polyclonal (IgG) to Human GFRA2
Human
IHC - Frozen, Western blot, ELISA
Unconjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal (IgG) to Human GFRA2
Human
IHC, Western blot, ELISA
Unconjugated

Details

Human GFRA2
Goat
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC (15 µg/ml)
  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA

Specificity and Use

GFRA2 antibody was raised against nS0-derived rhGFRa-2 extracellular domain.
Detects GDNF Family Receptor alpha 2 (rhGFR alpha-2).
Blockade of receptor-ligand interaction-Approximately 2-6 µg/ml of this antibody will block 50% of the binding of 2 ng/ml rhGDNF to immobilized rhGFRa-2/Fc Chimera (100 ul of a 1 µg/ml solution was coated in each well) in a functional ELISA assay. For direct ELISAs, the antibody can be used at 0.5-1.0 µg/ml with the appropriate secondary reagents to detect human GFRa-2. The detection limit for rhGFRa-2 is approximately 0.3 ng/well. For western blot analysis, the antibody can be used at 0.1-0.2 µg/ml with the appropriate secondary reagents to detect human GFRa-2. The detection limit for soluble rhGFRa-2 is approximately 5 ng/lane under non-reducing and reducing conditions. For immunohistochemistry, the antibody will detect GFRa-2 in paraffin-embedded tissue sections. The working dilution is 15 µg/ml.

Packaging

Lyophilized from 0.2 um sterile-filtered solution in PBS
1,000 µl 1 ml sterile PBS
Long term: -70°C; Short term: -20°C
For research use only.

About GFRA2

O00451 NM_001495 NP_001486.4

GFRA2 Antibody, GDNF receptor alpha-2 Antibody, GDNFRB Antibody, GFR-alpha 2 Antibody, GFR-alpha-2 Antibody, GDNF family receptor alpha-2 Antibody, GDNFR-beta Antibody, GDNF family receptor alpha 2 Antibody, Neurturin receptor alpha Antibody, RET ligand 2 Antibody, TRNR2 Antibody, TRN receptor, GPI-anchored Antibody, NTNR-alpha Antibody, NTNRA Antibody, GDNF receptor beta Antibody, GDNFR-alpha-2 Antibody, NRTNR-ALPHA Antibody, RETL2 Antibody

Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRa, which is a cell surface receptor for NTN. The cDNAs encoding NTNRa from human, rat, chicken, and mouse have been cloned recently (2-7).

Requested From: United States
Date Requested: 12/11/2016

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