Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
GFRA1 Antibody, GDNF receptor alpha-1 Antibody, GDNFRA Antibody, GFR-ALPHA-1 Antibody, GDNF family receptor alpha-1 Antibody, GDNFR Antibody, GDNFR-alpha-1 Antibody, RET ligand 1 Antibody, RETL1 Antibody, TRNR1 Antibody, RET1L Antibody, GDNF family receptor alpha 1 Antibody, GPI-linked anchor protein Antibody
Glial cell line-derived neurotrophic factor (GDNF) is a potent survival factor for central and peripheral neurons and is essential for the development of kidneys and the enteric nerves system. Physiological responses to GDNF require the presence of a novel glycosylphosphadidylinositol linked protein GDNFRa, which is a cell surface receptor for GDNF. The cDNAs encoding GDNFRa from human, rat, chicken and mouse have been cloned recently.
GFR alpha -1/GDNFR alpha -1 in Human Spinal Cord. GFR alpha -1/GDNFR alpha -1 was detected in immersion fixed paraffin-embedded sections of human spinal cord using Goat Anti-Human GFR alpha -1/GDNFR alpha -1 Antigen Affinity-purified Polyclonal Antibody at 15 ug/ml overnight at 4°C. Tissue was stained using Anti-Goat HRP-DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to ventral horn motor neurons.
Requested From: United States
Date Requested: 10/26/2016