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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GEN1 Antibody (aa60‑89) LS‑C166438
GEN1 antibody LS-C166438 is an unconjugated rabbit polyclonal antibody to GEN1 from human and mouse. Validated for WB.
Catalog
Size
Price
LS-C166438-400
400 µl
Unavailable

Popular GEN1 Products

Antibody
Species: Human, Mouse
Applications: Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: Western blot, ELISA
Antibody
Species: Human, Mouse
Applications: Western blot, ELISA

Product Description

GEN1 antibody LS-C166438 is an unconjugated rabbit polyclonal antibody to GEN1 from human and mouse. Validated for WB.
About GEN1
Endonuclease which resolves Holliday junctions by the introduction of symmetrically related cuts across the junction point, to produce nicked duplex products in which the nicks can be readily ligated. Four-way DNA intermediates, also known as Holliday junctions, are formed during homologous recombination and DNA repair, and their resolution is necessary for proper chromosome segregation. Q17RS7 NM_001130009 NP_001123481.1

GEN1 Antibody, Gen homolog 1, endonuclease Antibody, Gen Antibody


Specifications

Target
Human GEN1
Host
Rabbit
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E10162 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C166438. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa60-89
Specificity
This GEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human GEN1.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Customer Reviews (0)


Images


Western blot

Western blot of GEN1 Antibody in mouse liver tissue lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody.
Western blot of GEN1 Antibody in mouse liver tissue lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody.

Western blot

Western blot of GEN1 Antibody in MDA-MB435 cell line lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody;
Western blot of GEN1 Antibody in MDA-MB435 cell line lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody;

Western blot

Western blot of lysate from MDA-MB-453 cell line, using GEN1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
Western blot of lysate from MDA-MB-453 cell line, using GEN1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

Western blot

Western blot of GEN1 Antibody in mouse liver tissue lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody.
Western blot of GEN1 Antibody in mouse liver tissue lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody.

Western blot

Western blot of GEN1 Antibody in MDA-MB435 cell line lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody;
Western blot of GEN1 Antibody in MDA-MB435 cell line lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody;

Western blot

Western blot of lysate from MDA-MB-453 cell line, using GEN1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
Western blot of lysate from MDA-MB-453 cell line, using GEN1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

Western blot

Western blot of GEN1 Antibody in mouse liver tissue lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody.
Western blot of GEN1 Antibody in mouse liver tissue lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody.

Western blot

Western blot of GEN1 Antibody in MDA-MB435 cell line lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody;
Western blot of GEN1 Antibody in MDA-MB435 cell line lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody;

Western blot

Western blot of lysate from MDA-MB-453 cell line, using GEN1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
Western blot of lysate from MDA-MB-453 cell line, using GEN1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

Western blot

Western blot of GEN1 Antibody in mouse liver tissue lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody.
Western blot of GEN1 Antibody in mouse liver tissue lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody.

Western blot

Western blot of GEN1 Antibody in MDA-MB435 cell line lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody;
Western blot of GEN1 Antibody in MDA-MB435 cell line lysates (35 ug/lane). GEN1 (arrow) was detected using the purified antibody;

Western blot

Western blot of lysate from MDA-MB-453 cell line, using GEN1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.
Western blot of lysate from MDA-MB-453 cell line, using GEN1 Antibody. Antibody was diluted at 1:1000. A goat anti-rabbit IgG H&L (HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.


Requested From: 
Date Requested: 6/19/2018

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