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Anti-GDF5 / GDF-5 Antibody LS-C36583

Ordering

Wt. Vol. Conc. Price
500 µg 1000 µl - $650
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GDF5 / GDF-5 Antibodies

Anti-GDF5 / GDF-5 Antibody (aa28-41) IHC-plus™ LS-B808
Rabbit Polyclonal to Human GDF5 / GDF-5
Human
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-GDF5 / GDF-5 Antibody LS-C36583
Rat Monoclonal (IgG2b) to Mouse GDF5 / GDF-5
Mouse
ELISA, Functional Assay, Neutralization
Unconjugated

100% Guaranteed 100% Guaranteed
Rat Monoclonal (IgG2b) to Mouse GDF5 / GDF-5
Mouse
ELISA, Functional Assay, Neutralization
Unconjugated

Details

Mouse GDF5 / GDF-5
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2b Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • ELISA (0.5 - 1 µg/ml)
  • Functional Assay
  • Neutralization

Specificity and Use

GDF5 / GDF-5 antibody was raised against e. coli-derived monomeric rmGDF-5.
Recognizes mouse GDF-5 in direct ELISA. Does not cross-react with rmGDF-1, rmGDF-3, or rmGDF-8.
Suitable for use in direct ELISA and Neutralization. Neutralization (ND50): ~2-10 ug/ml in the presence of 3 ug/ml of rmGDF-5, using the ATDC5 cell line. Note: The exact concentration of antibody required to neutralize rmGDF-5 activity is dependent on the cytokine concentration, cell type, growth conditions and the type of activity studied. The Neutralization Dose50 (ND50) for this antibody is defined as that concentration of antibody required to yield one-half maximal inhibition of the cytokine activity on a responsive cell line, when that cytokine is present at a concentration just high enough to elicit a maximum response. Direct ELISA: 0.5-1.0 ug/ml. The detection limit is ~10 ng/well.

Packaging

Lyophilized from PBS, 5% trehalose.
1,000 µl Sterile PBS
Store at -20°C lyophilized. Once reconstituted, aliquot and store at -20°C.
For research use only.

About GDF5 / GDF-5

P43026 NM_000557 NP_000548.2

GDF5 Antibody, CDMP-1 Antibody, CDMP1 Antibody, GDF-5 Antibody, LAP4 Antibody, Radotermin Antibody, OS5 Antibody, BMP14 Antibody, SYNS2 Antibody

GDF5 / GDF-5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues.

Requested From: United States
Date Requested: 12/5/2016

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