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Anti-GBA / Glucosidase Beta Acid Antibody (clone 2e2) LS-C104954

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $355
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GBA / Glucosidase Beta Acid Antibodies

Anti-GBA / Glucosidase Beta Acid Antibody (aa352-536) LS-C185394
Rabbit Polyclonal (IgG) to Human GBA / Glucosidase Beta Acid
Human
IHC - Paraffin, ICC, Western blot
Unconjugated
Immunohistochemistry Image
Anti-GBA / Glucosidase Beta Acid Antibody (aa334-498) LS-C294223
Rabbit Polyclonal (IgG) to Human GBA / Glucosidase Beta Acid
Human
Western blot, ELISA
Unconjugated
Western blot Image
Anti-GBA / Glucosidase Beta Acid Antibody (aa117-214, Biotin) LS-C298413
Rabbit Polyclonal (IgG) to Human GBA / Glucosidase Beta Acid
Human
IHC - Paraffin, Western blot, ELISA
Biotin Conjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 2e2] (IgG2a,k) to Human GBA / Glucosidase Beta Acid
Human
Immunofluorescence, Western blot, ELISA
Unconjugated

Details

Human GBA / Glucosidase Beta Acid
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2a,k Monoclonal [2e2]
Unconjugated
Protein A purified
Unmodified

Applications

  • Immunofluorescence (10 µg/ml)
  • Western blot
  • ELISA

  • IHC - Paraffin

Specificity and Use

GBA / Glucosidase Beta Acid antibody was raised against gBA (NP_000148, 146 a.a. ~ 236 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Western Blot (Cell lysate) - positive control MCF-7. Western Blot (Transfected lysate) - positive control transfected 293T cell line. Immunofluorescence (10 ug/ml) - positive control HeLa cells. Sandwich ELISA (Recombinant protein).

Packaging

PBS, pH 7.2
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
For research use only.

About GBA / Glucosidase Beta Acid

P04062 NM_000157 NP_000148.2

GBA Antibody, Acid beta-glucosidase Antibody, Alglucerase Antibody, Beta-glucocerebrosidase Antibody, GBA1 Antibody, Glucosidase, beta, acid Antibody, GLUC Antibody, GCB Antibody, Lysosomal glucocerebrosidase Antibody, Metaxin Antibody, MTXN Antibody, Glucosylceramidase Antibody, Imiglucerase Antibody

GBA / Glucosidase Beta Acid encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Immunofluorescence

Immunofluorescence
Immunofluorescence of monoclonal antibody to GBA on HeLa cell (antibody concentration 10 ug/ml).

Western blot

Western blot
GBA monoclonal antibody (M01), clone 2E2 Western blot of GBA expression in MCF-7.

Western blot

Western blot
Western blot of GBA expression in transfected 293T cell line by GBA monoclonal antibody (M01), clone 2E2.

Enzyme-Linked Immunosorbent Assay

Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged GBA is approximately 1 ng/ml as a capture antibody.

Requested From: United States
Date Requested: 12/6/2016

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