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Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Gene Name: | growth arrest-specific 6 |
Synonyms: | GAS6, AXLLG, AXL stimulatory factor, AXSF, GAS-6, Growth arrest-specific 6 |
Target Sequences: | NM_000820 NP_000811.1 Q14393 |
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