Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse, Bovine (tested or 100% immunogen sequence identity)
Human, Rat (at least 90% immunogen sequence identity)
IHC - Frozen (1:10 - 1:50)
ELISA (1:50 - 1:100)
Specificity and Use
Galactocerebroside purified from bovine brain.
recognizes galactocerebroside, a surface antigen typically found on newly differentiated or developing oligodendrocytes. Staining of live cells prior to fixation will show a typical "patching" appearance. Cells fixed prior to staining will have a more solid, "smooth" appearance.
For live cell staining we recommend heat inactivation of the antisera to remove complement. The recommended fixative is 4% paraformaldehyde. Staining of live cells prior to fixation will show a typical "patching" appearance. Cells fixed prior to staining will have a more solid, "smooth" appearance.