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Anti-GABBR1 / GABA B Receptor 1 Antibody (aa947-961) IHC-plus™ LS-B4142

Note: This antibody replaces LS-C108332

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular GABBR1 / GABA B Receptor 1 Antibodies

Anti-GABBR1 / GABA B Receptor 1 Antibody (N-Terminus) IHC-plus™ LS-A5270
Rabbit Polyclonal to Human GABBR1 / GABA B Receptor 1
Human, Monkey, Mouse, Rat, Bovine, Hamster, Pig, Rabbit
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-GABBR1 / GABA B Receptor 1 Antibody (N-Terminus) IHC-plus™ LS-A5332
Rabbit Polyclonal to Human GABBR1 / GABA B Receptor 1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-GABBR1 / GABA B Receptor 1 Antibody (aa947-961) IHC-plus™ LS-B4142
Goat Polyclonal to Human GABBR1 / GABA B Receptor 1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
IHC - Paraffin
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human GABBR1 / GABA B Receptor 1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
IHC - Paraffin
Unconjugated

Details

Human GABBR1 / GABA B Receptor 1
Goat
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

IHC - Paraffin (3.75 - 5 µg/ml)

Specificity and Use

GABBR1 / GABA B Receptor 1 antibody was raised against synthetic peptide DRLSCDGSRVHLLYK from the C-terminus of human GABBR1 (NP_001461.1; NP_068703.1; NP_068704.2; NP_068705.2). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig (100%); Phytophthora (80%).
LS-E26947 - Lyophilized - 100 µg - $145.00
aa947-961
Human GABBR1. This antibody is expected to recognize reported isoforms a, b and c (NP_001461.1, NP_068703.1, NP_068704.2 resp.).
Immunohistochemistry: LS-B4142 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B4142 was determined to be 3.75 to 5 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About GABBR1 / GABA B Receptor 1

Q9UBS5 NM_001470 NP_001461.1

GABBR1 Antibody, DJ271M21.1.1 Antibody, DJ271M21.1.2 Antibody, GABA(B) receptor Antibody, Gaba-b-r1a Antibody, GABA-BR1 Antibody, Gaba-br1a receptor Antibody, GABAB, subunit 1c Antibody, GABAB1 Antibody, GABA-B receptor 1 Antibody, Gaba-b1 Antibody, Gababr1 receptor Antibody, GPRC3A Antibody, Gabab-receptor subunit 1a Antibody, GABABR1 Antibody, GABBR1-3 Antibody, GBR1 Antibody, HGB1a Antibody, GABA-B-R1 Antibody, GB1 Antibody

Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2. Within the heterodimeric GABA receptor, only GABBR1 seems to bind agonists, while GABBR2 mediates coupling to G proteins. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.

Immunohistochemistry

Immunohistochemistry
Anti-GABBR1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4142 concentration 3.75 ug/ml.
 

Requested From: United States
Date Requested: 12/6/2016

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