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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GAB2 Antibody (aa125‑174) IHC‑plus™ LS‑B7589
Note: This antibody replaces LS-C118339
GAB2 antibody LS-B7589 is an unconjugated rabbit polyclonal antibody to GAB2 from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B7589-50
50 µl
Unavailable

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Product Description

GAB2 antibody LS-B7589 is an unconjugated rabbit polyclonal antibody to GAB2 from human, mouse and rat. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues.
About GAB2
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. Q9UQC2 NM_012296 NP_036428.1

GAB2 Antibody, GRB2-associated binder 2 Antibody, KIAA0571 Antibody, Pp100 Antibody


Specifications

Target
Human GAB2
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:100)
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:40000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
GAB2 antibody was raised against synthetic peptide from human Gab2 (aa125-174).
Epitope
aa125-174
Specificity
Gab2 (Ab-159) Antibody detects endogenous levels of total Gab2 protein.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-GAB2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7589 dilution 1:100.
Anti-GAB2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7589 dilution 1:100.

Western blot

Western blot of extracts from COS cells, using Gab2 (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS cells, using Gab2 (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

Anti-GAB2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7589 dilution 1:100.
Anti-GAB2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7589 dilution 1:100.

Western blot

Western blot of extracts from COS cells, using Gab2 (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS cells, using Gab2 (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

Anti-GAB2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7589 dilution 1:100.
Anti-GAB2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7589 dilution 1:100.

Western blot

Western blot of extracts from COS cells, using Gab2 (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS cells, using Gab2 (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide.

Immunohistochemistry

Anti-GAB2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7589 dilution 1:100.
Anti-GAB2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7589 dilution 1:100.

Western blot

Western blot of extracts from COS cells, using Gab2 (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from COS cells, using Gab2 (Ab-159) Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/21/2018

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